The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 1993
Filed:
Sep. 06, 1991
Applicant:
Inventors:
Daniel Solomon, Edison, NJ (US);
James J Kaminski, Long Valley, NJ (US);
Steven K White, Leawood, KS (US);
Laura S Lehman de Gaeta, La Jolla, CA (US);
Ashit K Ganguly, Upper Montclair, NJ (US);
Assignee:
Schering Corporation, Kenilworth, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142362 ; 5142358 ; 5142355 ; 5142368 ; 5142372 ; 5142378 ; 5142382 ; 5142388 ; 5142392 ; 514 90 ; 544124 ; 544132 ; 544133 ; 544139 ; 544141 ; 544157 ; 544158 ; 544159 ; 544160 ; 544161 ; 544164 ; 544165 ; 544168 ; 544169 ; 544170 ; 544171 ; 544177 ;
Abstract
Novel 2,2-disubstituted glycerol-like compounds are disclosed for use as anti-allergic and anti-inflammatory compounds. The compounds are antagonists of platelet activating factor ('PAF'). Also disclosed are methods of synthesizing and using the compounds of the invention as well as pharmaceutical compositions thereof. The compounds have the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as defined in the specification.