The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 1993
Filed:
Nov. 19, 1990
Applicant:
Inventors:
Amleto Rizzi, Alte Ceccato, IT;
Gaetano Marchioro, Vicenza, IT;
Assignee:
FIS - Fabbrica Italiana Sintetici S.p.A., Vicenza, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07B / ;
U.S. Cl.
CPC ...
560-7 ; 562401 ; 562402 ; 562431 ;
Abstract
The present invention relates to a process for the separation of the enantiomers of threo-2-hydroxy-3-(2'- aminophenylthio)-3-(4'-methoxyphenyl)-propionic acid, which is an important intermediate in the synthesis of pharmacologically active compounds, by means of the direct crystallization of the relevant cyclohexylaminic salt. According to a preferred form of practical embodiment of the present invention, the optically pure acid is recovered as the hydrochloride of the corresponding methyl ester.