The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 1993
Filed:
Jun. 17, 1991
Muneo Saito, Hachioji, JP;
Yoshio Yamauchi, Hini, JP;
Nihon Bunko Kogyo Kabushiki Kaisha, Tokyo, JP;
Abstract
It is an object to provide a recycle chromatograph with supercritical fluid mobile phase for separating a sample into components by recycling a mobile phase which includes modifier solvent for the purpose of taking a desired component. It is structured in such a manner that a recycling pump (10), a column (14), a detector (16), and a three-way valve (18) are connected in a sequential order as described above to form a closed loop which acts as a recycle flow line. A back-pressure regulator (20) is connected to the remainder port (C) of this three-way valve (18), and a mobile phase supplying and pressurizing device (30, 38, 30A, 48) for supplying the mobile phase under a predetermined pressure is connected to a flow line between the three-way valve (18) and the recycling pump (10). By means of this mobile phase supplying and pressurizing device and the recycle closed loop, (the column pressure drop .DELTA.p)/(column plate number) can be reduced, whereupon the column effective plate number can be increased. Thus, a sufficient resolution rate for fractionating a component can be obtained after appropriate recycling times. Furthermore, by combining the mobile phase supplying device (30, 38 30A, 38A, 48) and the back-pressure regulator (20), the internal pressures in the column and the detector can be kept above the critical pressure even if unnecessary components are being removed or a necessary component is being fractionated. As a result of which fractionation can be performed.