The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 1992
Filed:
Aug. 05, 1991
Applicant:
Inventors:
H Holden Thorp, Cary, NC (US);
Neena Grover, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 27 ; 536 28 ; 536 29 ; 546-2 ;
Abstract
A method of cleaving nucleic acids comprises contacting a nucleic acid to an oxoruthenium(IV) coordination complex. Examples of coordination compounds useful for carrying out the method include Ru.sup.IV (tpy)(bpy)O.sup.2+, Ru.sup.IV (typ)(phen)O.sup.2+, Ru.sup.IV (typ)(tmen)O.sup.2+, Ru.sup.IV (bpy).sub.2 (py)O.sup.2+, and Ru.sup.IV (phen).sub.2 (py)O.sup.2+.