The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 1992

Filed:

Dec. 07, 1990
Applicant:
Inventors:

Mary K Shriver, Bellevue, WA (US);

Larry H Gosting, Snohomish, WA (US);

Edna S Dickinson, Seattle, WA (US);

Janela McClure, City of Vashon Is., WA (US);

Elaine K Thomas, Seattle, WA (US);

Wesley L Cosand, Bothell, WA (US);

Assignee:

Bristol-Myers Squibb Company, New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; C12N / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
435-5 ; 435 7021 ; 4351722 ; 43524027 ; 5303881 ; 53038835 ; 5303894 ; 530864 ; 530868 ; 424 858 ; 424 86 ;
Abstract

Methods and composition for HIV diagnosis and treatment using monoclonal antibodies reactive with one or more neutralizing regions of HIV proteins, using the peptides or homologs thereof from that region, and using related nucleic acid segments. Exemplary neutralizing regions include selected portions of the env and gag genes from various HIV isolates. Monoclonal antibody secreting cell lines include HIV-gp110-1, -2, -3, -4, -5 and -6 (A.T.C.C. Accession Nos. HB9175, HB9176, HB9177, HV9405, HB9406 and HB9404, respectively) and HIV-p25-2, -3, -6 and -7 (A.T.C.C. Accession Nos. HB9407, HB9408, HB9409 and HB9410, respectively).


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