The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1992
Filed:
Jan. 12, 1990
Applicant:
Inventors:
Patricia E Shewen, Ontario, CA;
Bruce N Wilkie, Ontario, CA;
Assignee:
University of Guelph, , CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12P / ; C12N / ;
U.S. Cl.
CPC ...
424 88 ; 424 92 ; 435 713 ; 4352521 ;
Abstract
A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum-free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic immunity to pneumonic pasterellosis.