The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1992
Filed:
Aug. 17, 1990
Applicant:
Inventors:
Johan Selmer, Farum, DK;
Niels Tromholt, Charlottenlund, DK;
Assignee:
Novo Nordisk A/S, , DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424-11 ; 424-9 ;
Abstract
A diagnostic reagent for the detection in vivo of increased release of a fibrinolytic enzyme or increased fibrinolytic activity in the human or animal body comprises an antibody reactive with a fibrinolytic enzyme, or a biologically active fragment of the antibody, labelled with a substance which permits the detection in vivo of binding of the antibody to the fibrinolytic enzyme. In one embodiment, increased clearance of the antibody is provided by subsequent administration of the fibrinolytic enzyme with which the antibody is reactive. The fibrinolytic enzyme is preferably t-PA.