The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 1992

Filed:

Apr. 09, 1991
Applicant:
Inventors:

George S Wilson, Lawrence, KS (US);

Dilbir S Bindra, Lawrence, KS (US);

Brian S Hill, Lawrence, KS (US);

Daniel R Thevenot, Paris Cedex, FR;

Robert Sternberg, Thiais, FR;

Gerard Reach, Paris Cedex, FR;

Yanan Zhang, Lawrence, KS (US);

Assignee:

The University of Kansas, Lawrence, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B / ;
U.S. Cl.
CPC ...
128635 ; 204403 ; 204415 ;
Abstract

Implantable enzymatic sensors (25, 43, 44) for biochemicals such as glucose are provided having an ideal size and geometry for optional long term implantation and linear responses over the concentration ranges of interest. The sensors (25, 43, 44) include an elongated body (10, 26, 46) supporting an indicating electrode section having an appropriate enzyme immobilized thereon to present an enzymatic indicating surface (21, 33, 54). A permeable synthetic polymer membrane (24, 42, 56) is applied over the sensor body (10, 26, 46) to protect the enzyme and regulate diffusion of analyte therethrough, to ensure linearity of sensor response. The sensors (25, 43) are of flexible design and can be implanted using a catheter. Alternately, the sensor (44) includes an internal indicating electrode body (46) housed within an apertured, hollow needle (48). A holder (66) affixed to the needle (48) allows for easy manipulation and implantation of the sensor (44).

Published as:
CA2080022A1; WO9115993A1; AU7782891A; US5165407A; EP0525127A1; AU640785B2; JPH05506172A; EP0525127A4; CA2080022C; EP0525127B1; ATE194062T1; DE69132270D1; DK0525127T3; ES2148154T3; DE69132270T2; GR3034376T3; JP3194434B2;

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