The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1992

Filed:

May. 19, 1987
Applicant:
Inventors:

Pascal Bailon, Florham Park, NJ (US);

John E Smart, Weston, MA (US);

David V Weber, Nutley, NJ (US);

Assignee:

Hoffmann-La Roche, Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C07K / ; G01N / ;
U.S. Cl.
CPC ...
5303882 ; 5303892 ; 5303911 ; 5303915 ; 53038823 ; 530351 ; 530402 ; 530403 ; 530404 ; 530405 ; 530406 ; 530409 ; 530410 ; 530411 ; 530412 ; 530413 ; 530810 ; 530811 ; 530812 ; 530813 ; 530814 ; 530417 ; 530422 ; 435-71 ; 435-78 ; 435 691 ; 436501 ; 436518 ; 436524 ; 436527 ; 436528 ; 436529 ; 436530 ; 536 56 ; 536112 ;
Abstract

Methods are provided for the purification of interleukin-2 (IL-2) from a wide variety of sources, including synthetic mixtures, culture medium conditioned by natural IL-2 producing cells, and mammalian and bacterial recombinant IL-2 expression systems. The methods of the invention employ IL-2 receptor-affinity adsorbents in which soluble IL-2 receptors have been immobilized on solid supports. Through the use of these affinity adsorbents, highly purified IL-2 can be produced in a single step from bacterial extracts or conditioned medium. The IL-2 thus purified is largely free of aggregated forms, which are often present when other purification methods are used.


Find Patent Forward Citations

Bailon, Pascal. (1992). Purification of interleukin-2 by receptor-affinity chromatography (U.S. Patent No. 5162503). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5162503

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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