The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1992
Filed:
Aug. 20, 1990
Applicant:
Inventors:
Claudio Semeraro, Bresso, IT;
Dino Micheli, Modena, IT;
Daniele Pieraccioli, Verona, IT;
Giovanni Gaviraghi, Verona, IT;
Alan D Borthwick, London, GB;
Assignee:
Glaxo, S.p.A., Verona, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514356 ; 546321 ; 546283 ; 546194 ; 544 60 ; 544124 ; 544360 ; 514343 ; 514318 ; 514218 ; 5142355 ; 5142278 ;
Abstract
Compounds are described of the formula: ##STR1## and physiologically acceptable salts thereof, in which R.sub.1 -R.sub.7 are defined hereinafter. The compounds represented by formula (I) reduce intracellular calcium ion concentration by limiting transmembranal calcium ion concentration and thus may be useful for the treatment of cardiovascular disorders such as hypertension.