The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 1992
Filed:
Oct. 16, 1990
Applicant:
Inventors:
Donald F Wallach, Hollis, NH (US);
Rajiv Mathur, Nashua, NH (US);
Assignee:
Micro Vesicular Systems, Inc., Nashua, NH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; B01J / ;
U.S. Cl.
CPC ...
264-43 ; 424450 ; 4284022 ;
Abstract
A new 'cold-loading' technique for filling the amorphous central cavity of paucilamellar lipid vesicles with a water immiscible material has been developed. Preformed, substantially aqueous filled paucilamellar lipid vesicles are mixed with the water immiscible material to be encapsulated under intermediate mixing conditions, thereby replacing the aqueous solution with the water-immiscible solution. The 'cold-loading' technique is particularly useful for encapsulation of volatiles and heat labile materials.