The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 1992

Filed:

Nov. 22, 1989
Applicant:
Inventor:

Tadatsugu Taniguchi, Ibaraki-shi, Osaka 567, JP;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 27 ;
Abstract

The inhibition or control of expression of IL-2 or IL-2.alpha. genes, and the inhibition or control of fundamental cellular processes responsible for retroviral replication, in particular HIV-I and HTLV-I DNA molecules, are disclosed. The invention is directed to nucleic acids or nucleic acid compositions which competitively bind regions of the IL-2 or IL-2.alpha. genes corresponding to their respective transcription factors. DNA or RNA fragments spanning the following regions in the IL-2 gene are shown to be effective; -195 to -204; -115 to -164; and -165 to -222. DNA or RNA fragments spanning the following regions in the IL-2.alpha. gene are shown to be effective: -62 to -71; and -32 to -86. Compositions comprising combinations of these fragments are also disclosed.


Find Patent Forward Citations

Loading…