The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 1992
Filed:
Sep. 07, 1989
Applicant:
Inventor:
Phillip Friden, Bedford, MA (US);
Assignee:
Alkermes, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
424 8591 ; 424 852 ; 424 858 ; 424 943 ; 435188 ; 530302 ; 530311 ; 530370 ; 530351 ; 53038822 ; 5303911 ; 5303913 ; 5303915 ; 5303917 ; 5303919 ; 530399 ;
Abstract
The present invention pertains to a method for delivering a neuropharmaceutical agent across the blood brain barrier to the brain of a host. The method comprises administering to the host a therapeutically effective amount of an antibody-neuropharmaceutical agent conjugate wherein the antibody is reactive with a transferrin receptor. Other aspects of this invention include a delivery system comprising an antibody reactive with a transferrin receptor linked to a neuropharmaceutical agent and method for treating hosts afflicted with a disease associated with a neurological disorder.