The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1992
Filed:
Feb. 06, 1989
Applicant:
Inventors:
Steven P Brown, Bude, GB;
Anthony L Cooper, Bude, GB;
Jethro L Longridge, Macclesfield, GB;
Jeffrey J Morris, Sandbach, GB;
John Preston, Knutsford, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
514646 ; 514450 ; 514452 ; 514466 ; 514510 ; 514524 ; 514538 ; 514568 ; 514569 ; 514585 ; 514603 ; 514604 ; 514605 ; 514617 ; 514618 ; 514629 ; 514656 ; 514657 ; 514709 ; 514710 ; 549348 ; 549349 ; 549350 ; 549358 ; 549359 ; 549366 ; 549432 ; 549433 ; 549443 ; 558413 ; 560 10 ; 560 12 ; 560 24 ; 560 28 ; 562427 ; 562430 ; 564 85 ; 564 92 ; 564 99 ; 564162 ; 564184 ; 564218 ; 564222 ; 564427 ; 564428 ; 564440 ; 568 29 ; 568 30 ;
Abstract
The invention concerns novel pharmaceutical compositions for use in the treatment of certain complications of diabetes and galactosemia and which contain a nitromethane derivative (or its non-toxic salt) as active ingredient. The nitromethane derivatives are inhibitors of the enzyme aldose reductase. Many of the inhibitors are novel and are provided, together with processes for their manufacture and use, as further features of the invention.