The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 1992
Filed:
Jul. 12, 1991
Itsuo Uchida, Yokohama, JP;
Akira Saito, Yokohama, JP;
Akihiro Yasuda, Yokohama, JP;
Kunio Iwata, Hatano, JP;
Hiroaki Hari, Tokushima, JP;
Katsuyoshi Hara, Yokohama, JP;
Mutsuyoshi Matsushita, Hatano, JP;
Koretake Anami, Nakatsu, JP;
Junichi Haruta, Yokohama, JP;
Noboru Furukawa, Hatano, JP;
Japan Tobacco Inc., Tokyo, JP;
Yoshotomi Pharmaceutical Industries, Ltd., Osaka, JP;
Abstract
Novel peptide derivatives of the following formula ##STR1## wherein each symbol is as defined in the specification, pharmaceutically acceptable acid addition salts thereof and analogous copounds thereof. Since the derivatives and their pharmaceutically acceptable acid addition salts of the present invention possess stronger actions on central nervous system (e.g. antagonistic action against hypothermia, locomotor stimulant action, signal reflex stimulant action), they are of use as a therapeutic medicament for central nervous disorders such as impaired consciousness, depression, hypomnesia, the like in association association with schizophrenia, melancholia, senile dementia, sequelae of cerebrovascular disorders, head trauma, epilepsy and spinocerebellar degeneracy.