The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 1992

Filed:

May. 21, 1990
Applicant:
Inventors:

William E Brown, Grayslake, IL (US);

John M Clemens, Gurnee, IL (US);

Sharon M Devereaux, Gurnee, IL (US);

John G Hofler, Ingleside, IL (US);

Kevin M Knigge, Wheeling, IL (US);

Sarah E Safford, Libertyville, IL (US);

Assignee:

Abbott Laboratories, North Chicago, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435-5 ; 435-734 ; 435-792 ; 435 36 ; 435970 ; 435971 ; 436518 ; 436527 ; 436528 ; 436531 ; 436535 ; 436530 ; 422 56 ; 422 58 ; 422 60 ; 422 61 ;
Abstract

A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having an average diameter of from about 0.1 to about 5 microns. The particles are retained and immobilized upon the fibers of the matrix. Preferably, the particles have on their surfaces a substance capable of reaction with the analyte in the sample, and the average diameter of the particles is less than the average pore size of the matrix. The device, in a preferred embodiment, comprises a substantially planar layer of the described material.


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