The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 1992
Filed:
Dec. 05, 1991
Applicant:
Inventors:
Harry A Albrecht, Towaco, NJ (US);
Ka-Kong Chan, Hopatcong, NJ (US);
Dennis D Keith, Montclair, NJ (US);
Rudolf L Then, Weil, DE;
Manfred Weigele, North Caldwell, NJ (US);
Assignee:
Hoffmann La-Roche, Inc., Nutley, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514202 ; 514201 ; 514206 ; 540221 ; 540222 ; 540225 ; 540226 ;
Abstract
There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula ##STR1## wherein R.sub.1 is an antibiotically active quinolonyl; R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, amino, lower alkylthio and amido; R.sub.3 is selected from the group consisting of hydrogen, and acyl group, and m is 0, 1 or 2 and the readily hydrolysable esters or salts of these compounds and hydrates of the compounds of formula I or of their esters or salts.