The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 1992
Filed:
Nov. 02, 1990
Applicant:
Inventors:
Bor-Sheng Lin, Berkeley Heights, NJ (US);
H Kenneth Spencer, Chatham, NJ (US);
Joseph W Scheblein, Flemington, NJ (US);
Assignee:
Anaquest, Inc., Libery Corner, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
546208 ; 546187 ; 546190 ; 546191 ; 546193 ; 546194 ; 546196 ; 546197 ; 546198 ; 546199 ; 546200 ; 546201 ; 546202 ; 546209 ; 546210 ; 546211 ; 546212 ; 546213 ; 546223 ; 546224 ; 544323 ; 544326 ; 544324 ; 544227 ; 544284 ;
Abstract
The present invention is directed to a method for preparing a 4-alkoxyalkyl-4-phenylaminopiperidine compound which comprises the steps of (a) reacting an N-substituted-4-piperidone compound with an aniline compound to form a Schiff base compound, (b) reacting the Schiff base compound with an anionic reagent having an anion stabilizing group to form an amine compound, and (c) reducing the amine compound in step (b) with a reducing agent to displace the anion stabilizing group. The anionic reagent in step (b) above has the general formula: