The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 1992

Filed:

Oct. 20, 1989
Applicant:
Inventors:

Pia Lading, Gentofte, DK;

Yvonne Lundsholm, Oxie, SE;

Tomas Norling, Copenhagen, DK;

Assignee:

A/S Dumex (Dumex Ltd.), Copenhagen, DK;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514396 ; 424435 ; 424423 ; 424484 ; 4241951 ; 514943 ; 514944 ; 514964 ;
Abstract

Controlled delivery of biologically active agents such as pharmaceuticals to body sites is accomplished by combination with a monoglyceride and a vegetable oil. Upon contact with an aqueous liquid, the composition forms a reverse hexagonal liquid crystalline phase matrix which releases the active agent in controlled fashion. The method of delivery is particularly useful for the treatment of periodontal disease by insertion of the liquid crystalline phase precursor composition directly into the periodontal pocket, where water from the gingival fluid induces the spontaneous in situ formation of the reverse hexagonal liquid crystalline phase matrix.


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