The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 1992
Filed:
Jul. 25, 1990
Applicant:
Inventors:
George C Rovnyak, Hopewell, NJ (US);
Spencer D Kimball, East Windsor, NJ (US);
Assignee:
E. R. Squibb & Sons, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514212 ; 5142285 ; 5142328 ; 514267 ; 540600 ; 544 60 ; 544115 ; 544229 ; 544250 ; 544311 ; 556418 ; 556427 ; 568 62 ; 568 65 ; 568424 ; 568705 ;
Abstract
A compound of the formula ##STR1## (symbols defined in the specification), its 3,4-dihydropyrimidine tautomer form and pharmaceutically acceptable salts thereof have calcium entry blocking activity. A process of preparation, pharmaceutical composition and method of using the compound to reduce blood pressure are also provided.