The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 1992

Filed:

Dec. 13, 1988
Applicant:
Inventors:

David Botstein, Brookline, MA (US);

Ronald W Davis, Menlo Park, CA (US);

Gerald R Fink, Brookline, MA (US);

Alison Taunton-Rigby, Lincoln, MA (US);

Robert G Knowlton, Lexington, MA (US);

Jen-i Mao, Bedford, MA (US);

Donald T Moir, Waltham, MA (US);

Christopher G Goff, Haverford, PA (US);

Assignee:

Collaborative Research, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C07H / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 536 27 ; 4353201 ; 435256 ; 435942 ; 435 695 ; 435 699 ; 435226 ; 435 6951 ; 435 694 ; 435 696 ; 4351723 ; 435 711 ; 935-6 ; 935 37 ; 935 60 ; 935 69 ;
Abstract

A DNA segment contains a GAL1 promoter of Saccharomyces cerevisae linked to a gene other than the galoctokinase gene, for directing the expression of the gene within a yeast cell. A GAL1 promoter portion of Saccharomyces cerevisae is linked to a foreign DNA segment for use in expressing a desired protein. Yeast cells containing the GAL1 promoter linked to a foreign DNA segment are grown in a medium containing glucose, wherein the yeast cells metabolize the glucose and are permitted to express a polypeptide when galactose is present in the medium.


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