The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 1992
Filed:
Jun. 19, 1990
Pierre Duhamel, Mont Saint Aignan, FR;
Lucette Duhamel, Mont Saint Aignan, FR;
Denis Danvy, Cany Barville, FR;
Jean-Christophe Plaquevent, Notre Dame De Bondeville, FR;
Bruno Giros, Kremlin Bicetre, FR;
Claude Gros, Paris, FR;
Jean-Charles Schwartz, Paris, FR;
Jeanne-Marie Lecomte, Paris, FR;
Societe Civile Bioprojet, Paris, FR;
Abstract
The (R) or (S) isomer of acetorphan or N-12-acetylthiomethyl-1-oxo-3-phenyl propyl/(S) alanine methyl ester is prepared by splitting of racemic 3-acetylthio-2-benzyl propanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.