The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 1992
Filed:
Aug. 15, 1988
Applicant:
Inventors:
David C Anderson, Seattle, WA (US);
A C Morgan, Jr, Edmonds, WA (US);
Paul G Abrams, Seattle, WA (US);
Assignee:
NeoRx Corporation, Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424-11 ; 424-9 ; 424 8591 ; 424 943 ; 514-8 ; 514 12 ; 514 21 ; 530395 ; 5303917 ; 5303897 ; 53028815 ; 5303888 ; 5303871 ; 5303913 ; 435188 ;
Abstract
Covalently-linked complexes (CLCs) for targeting a defined population of cells, comprising a targeting protein or peptide; a cytotoxic agent; and an enhancing moiety, wherein the enhancing moiety is capable of promoting CLC-membrane interaction are disclosed. Methods for using the claimed CLCs to obtain enhanced in vivo cytotoxicity and enhanced in vivo imaging are also described.