The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 1992
Filed:
Jan. 14, 1991
Applicant:
Inventors:
William C Mobley, Moraga, CA (US);
Frank M Longo, San Francisco, CA (US);
James C Kauer, Kennett Square, PA (US);
Assignee:
Regents of the University of California, Berkeley, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
514 14 ; 514 15 ; 514 16 ; 514 17 ; 514 18 ; 530326 ; 530327 ; 530328 ; 530329 ; 530330 ; 530839 ; 930120 ; 930D / ;
Abstract
The present invention provides both agonist and antagonist nerve growth factor peptides. The NGF blocking peptides can be used to inhibit the expression of mRNA and their encoded proteins whose expression is stimulated by NGF, such as .beta.-protein precursor and prion proteins, which proteins or their products are associated with neurodegenerative disorders, whereas the NGF agonist peptides can be used to treat neoplastic disorders such as neuroblastomas.