The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 1992

Filed:

Apr. 09, 1991
Applicant:
Inventors:

Yoshikazu Morishita, Kanagawa, JP;

Mitsuru Takahashi, Tokyo, JP;

Koji Yamada, Shizuoka, JP;

Tomoyuki Sano, Tokyo, JP;

Isao Kawamoto, Kanagawa, JP;

Katsuhiko Ando, Tokyo, JP;

Hiroshi Sano, Tokyo, JP;

Yutaka Saito, Tokyo, JP;

Hiroshi Kase, Tokyo, JP;

Yuzuru Matsuda, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12D / ;
U.S. Cl.
CPC ...
424118 ; 435171 ;
Abstract

Compounds comprising a linear .beta.1.fwdarw.6 glucan esterified by caproic acid, the number of D-glucose residues being from 7 to 40 and the number of caproic acid residues being from 2 to 30, may be be obtained by fermentation of a microorganism of the genus Aureobasidium. These compounds are designated HS-142-1. Preferred microorganism is Aureobasidium pullulans var. melanigenum KAC-2383 (FERM-BP 2407). The compounds of the present invention exhibit excellent antagonistic activity to ANP and are capable of inhibiting the bonding of ANP to ANP receptors.


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