The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 1992

Filed:

Dec. 11, 1990
Applicant:
Inventors:

Gilbert Regnier, Chatenay Malabry, FR;

J F Benaud De La Faverie, Le Chesnay, FR;

Alain Lombet, Champigny, FR;

Jean-Pierre Iliou, Puteaux, FR;

Jean-Paul Vilaine, Chatenay Malabry, FR;

Jean-Pierre Bidouard, Chilly Mazarin, FR;

Albert Lenaers, Triel Sur Seine, FR;

Assignee:

Adir et Compagnie, Courbevoie, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514327 ; 514320 ; 514324 ; 546192 ; 546196 ; 546202 ; 546216 ; 546217 ;
Abstract

The compounds disclosed are 1-R'-4-RS-piperidines in which R' and R, which are different, may each represent: (1) (alkoxybenzyl)-alkyl or -alkenyl, or (2) (optionally-substituted chromanyl-, thiochromanyl-, chromenyl- or thiochromenyl)-alkyl or -alkenyl. The compounds are useful in the treatment of disorders associated with tissue ischaemia and of peripheral vascular disorders or in the treatment of disorders in which lipid peroxidation plays an initiating and/or aggravating role. A typical disclosed compound is: 4-(2,3,4-tirmethoxybenzylthio)-1-(3,5-di- tert-butyl-4-hydroxybenzyl)piperidine. ,3,4-trimethoxybenzylthio)-1-(3,5-di-tert-butyl-4-hydroxybenzyl)piperidine .


Find Patent Forward Citations

Loading…