The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 1992
Filed:
Apr. 16, 1991
Applicant:
Inventors:
John Collins, Braunschweig, DE;
Helmut Blocker, Braunschweig, DE;
Ronald Frank, Wolfenbuettel, DE;
Friedhelm Maywald, Braunschweig, DE;
Hans Fritz, Hohenbrunn, DE;
Wolfgang Bruns, Wuppertal, DE;
Assignee:
Bayer Aktiengesellschaft, Leverkusen, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
514 12 ; 514-9 ; 514-2 ; 930250 ; 930260 ; 930270 ; 530324 ; 530325 ; 530350 ; 435 692 ; 435 691 ;
Abstract
The present invention relates to a peptide having essentially the amino acid sequence of pancreatic secretory trypsin inhibitor (PSTI). The present invention also relates to variants of such peptide wherein one or more of the amino acids in the original sequence are replaced by other amino acids. These peptides show an advantageously modified specificity in their inhibotory action. A method of preparation of the peptides and their pharmaceutical use is also described.