The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 1992

Filed:

May. 05, 1989
Applicant:
Inventors:

George N Paradissis, St. Louis, MO (US);

James A Garegnani, Ballwin, MO (US);

Roy S Whaley, St. Louis, MO (US);

Assignee:

KV Pharmaceutical Company, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424451 ; 424456 ; 424458 ; 424459 ; 424460 ; 424461 ; 424462 ; 424463 ; 514929 ; 514962 ; 514963 ;
Abstract

A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core composed of a pharmaceutically acceptable, film forming polymer. The film forming polymer is effective to permit release of the organic nitrate from the spheres, over a daily dosing period, at a rate that achieves a therapeutically effective level of the organic nitrate, while effecting a drug holiday towards a latter portion of the daily dosing period so as not to induce tolerance.


Find Patent Forward Citations

Paradissis, George. (1992). Oral once-per-day organic nitrate formulation which does not induce (U.S. Patent No. 5122384). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5122384

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…