The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 1992

Filed:

Oct. 23, 1989
Applicant:
Inventors:

John M McCall, Kalamazoo, MI (US);

Donald E Ayer, Kalamazoo, MI (US);

E Jon Jacobsen, Plainwell, MI (US);

Frederick J VanDoornik, Hamilton, MI (US);

John R Palmer, Kalamazoo, MI (US);

Assignee:

Upjohn, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544123 ; 546227 ; 546 14 ; 546 22 ; 546197 ; 546210 ; 544377 ; 544370 ; 544406 ; 544372 ; 544364 ; 544365 ; 544360 ; 544357 ; 544337 ; 544229 ; 544295 ; 544 69 ; 544 53 ; 544 54 ; 544 55 ; 544 57 ; 544 581 ; 544 584 ; 544 585 ; 544 586 ; 544 60 ; 544 62 ; 544 83 ; 544 96 ; 544113 ; 544 82 ; 544121 ; 544205 ; 544206 ; 544207 ; 544182 ; 544208 ; 544209 ; 544211 ; 544212 ; 544194 ; 544210 ; 544213 ; 544195 ; 544214 ; 544216 ; 544217 ; 544218 ; 544219 ; 544366 ; 544376 ; 544373 ; 544368 ; 544238 ; 544232 ; 544243 ; 544316 ; 544317 ; 544318 ; 544319 ; 544320 ; 544321 ; 544324 ; 544327 ; 544328 ; 544331 ; 544333 ; 544122 ; 544405 ; 540542 ; 540604 ; 540596 ; 540608 ; 540480 ; 540481 ; 540483 ; 540450 ; 540598 ; 536 23 ; 536 24 ; 536 31 ; 548406 ; 548413 ; 548526 ; 548535 ; 548336 ; 548112 ;
Abstract

The aromatic amines (I), alkyl amines (II), bicyclic amines (III). ##STR1## cycloalkyl amines (IV), aromatic bicyclic amines (V), hydroquinone amines (VI), quinone amines (VII), amino-ethers (VIII) and bicyclic amino ethers (IX) are useful as pharmaceutical agents for treating a number of conditions including spinal trauma, mild and/or moderate to severe head injury, etc. Also disclosed is a method of treatment using the 3,4-dihydrobenzopyrans (XI).


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