The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 09, 1992
Filed:
Sep. 20, 1989
Applicant:
Inventors:
Ian G Fotheringham, Wheeling, IL (US);
Jennifer Nelms, Des Plaines, IL (US);
Assignee:
The NutraSweet Company, Deerfield, IL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 27 ; 536 28 ; 536 29 ;
Abstract
Disclosed are DNA sequences bonding deletion, substitution and/or addition analogs of the E. coli enzyme, chorismate mutase/prephenate dehydratase (CMPD). Preferred expression products include [des-Gln.sup.307, des-Ala.sup.308, des-Gly.sup.309, des-Ala.sup.310 ]CMPD; [Leu.sup.306 ]CMPD; [des-Thr.sup.304, Lys.sup.305, des-Gln.sup.306 ]CMPD; and [Cys.sup.309 ]CMPD display enzymatic activity of the wild type enzyme but are more resistant to inhibition in the presence of phenylalanine.