The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 09, 1992

Filed:

Nov. 28, 1989
Applicant:
Inventors:

Stuart F Schlossman, Newton Center, MA (US);

Chikao Morimoto, Needham, MA (US);

Assignee:

Coulter Corporation, Hialeah, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; G01N / ;
U.S. Cl.
CPC ...
435-724 ; 424-11 ; 424 8591 ; 435-79 ; 435 34 ; 4351722 ; 43524027 ; 435948 ; 436548 ; 530809 ; 53038875 ; 53038873 ; 5303887 ; 935110 ;
Abstract

A monoclonal antibody which binds preferentially to a subset of the human CD4+ lymphocyte population whereby to positively and precisely distinguish between helper-inducer and suppressor-inducer cells in the CD4+ cell population. The monoclonal antibody recognizes a novel antigen on the CD4+ lymphocytes by means of which it can bind CD4+ cells which express the antigen on the surface of CD4+ cells. The CD4+ subset cell population to which this antibody preferentially binds is the CD4+ helper-inducer population. This selectivity of the monoclonal antibody enables cell sorting, diagnostic and possible therapeutic applications thereof to be realized. The monoclonal antibody also reacts with CD8 cells, B cells and macrophages.


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