The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 02, 1992
Filed:
Oct. 26, 1990
Robert L Coleman, Framingham, MA (US);
Chung C Young, Weston, MA (US);
Nova Biomedical Corporation, Waltham, MA (US);
Abstract
An apparatus for correcting an initial measurement of the concentration of a first water soluble species dissolved in a water-based component of a biological fluid that also includes a second water soluble species and a volume occupying component, the initial measurement having been taken using an original sample of the fluid that had been diluted by an amount of additional aqueous solution to form a diluted sample is disclosed; the concentration of the second water soluble species is measured in an undiluted sample of the biological fluid to obtain a direct concentration and is measured using a diluted sample of the fluid to obtain an indirect concentration, and the initial measurement of concentration of the first species is adjusted based on a combination of the direct and indirect concentration determination of the second species. The apparatus includes a first measurement device, which may be a colorimeter or amperometer, for measuring the diluted first species concentration; a second measurement device, which may be an indirect potentiometer, for measuring the diluted second species concentration; a third measurement device, which may be an ion selective electrode, for measuring the undiluted second species concentration; in particular embodiments, additional measurement devices, which may be a gas sensor and a spectrophotometer, for measuring the concentration of species which may complex with second species, and a computer connected to the various measurement devices.