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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5110736 B1

PDFFull Text
Date of Patent:
May. 05, 1992

Filed:

Oct. 24, 1990

Purificaiton procedure of tpa from crude preparations

Applicant:
Inventors:

Mitsuyoshi Morii, Yokohama, JP;

Masaharu Ohoka, Yokohama, JP;

Nobuhiro Kawashima, Sagamihara, JP;

Noriko Morii, Yokohama, JP;

Toshihiko Suzuki, Tokyo, JP;

Assignee:

Mitsui Toatsu Chemicals, Incorporated, Tokyo, JP;

Attorney:

Nixon & Vanderhye

Primary Examiner:

Charles L Patterson

Int. Cl.
CPC ...
C12N / ;
U.S. Cl.
CPC ...
435226 ; 435212 ; 435219 ;
Abstract

Crude tPA containing, as an impurity, a protein which is reactive with an anti-human tPA antibody and has a molecular weight of 110,000.+-.20,000 daltons is purified by bringing the crude tPA into close contact with an affinity reagent containing an immobilized Kunitz inhibitor which is produced in seeds of Erythrina latissima and other Erythrina plants and acts as an inhibitor on trypsin, plasmin and tPA but does not act on urokinase, so that tPA is collected selectively.

Find Patent Forward Citations

Morii, Mitsuyoshi. (1992). Purificaiton procedure of tpa from crude preparations (U.S. Patent No. 5110736). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5110736

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