The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 1992
Filed:
Jun. 13, 1990
Applicant:
Inventor:
Eric F Fisher, Boulder, CO (US);
Assignee:
Amgen, Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435119 ; 4351721 ; 43525233 ; 4353201 ; 536 27 ; 935-9 ; 935 41 ; 935 60 ;
Abstract
A system for the production of biotin wherein a biotin retention-deficient strain of a cell is transformed with plasmid bearing the biotin gene cluster bio (A, B, F, C and D). The media of cultures of the resulting cells contains enhanced amounts of biotin by comparison with similar constructions in strains capable of biotin retention.