The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 1992
Filed:
Mar. 14, 1990
Sandor Erdos, Budapest, HU;
Jozsef Kenderfi, Budapest, HU;
Erzsebet Barczay, Budapest, HU;
Aranka Hegedus nee Szima, Budapest, HU;
Maria Krisztian, Budapest, HU;
Attila Mandi, Budapest, HU;
Eva Tajthy nee Juhasz, Budapest, HU;
Peter Tompe, Budapest, HU;
Margit Csorgo, Budapest, HU;
Marton Fekete, Budapest, HU;
Frigyes Gorgenyi, Budapest, HU;
Zoltan Torma, Budapest, HU;
EGIS Gyogyszergyar, , HU;
Abstract
The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyridin e (referred to further on as 'nifedipine') as active ingredient which comprises admixing a solution or solutions of 1 part by weight of nifedipine, 0.1-1.5 parts by weight of one or more hydrophilizing agent(s) and 0.05-1.5 parts by weight of one or more retarding agent(s) formed with one or more identical or different solvent(s) completely or partly and applying the solution(s) thus obtained simultaneously or in succession onto an inert carrier, drying and sieving the product thus obtained and subsequently admixing the same with suitable conventional auxiliary agents and compressing the mixture thus obtained to tablets in a known manner and coating the tablets or filling the mixture into capsules.