The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 1992
Filed:
Apr. 28, 1989
Applicant:
Inventors:
Steven P Brown, Bude, GB;
Anthony L Cooper, Bude, GB;
Jethro L Longridge, MacClesfield, GB;
Jeffrey Morris, Sandbach, GB;
John Preston, Knutsford, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514443 ; 549 42 ; 549 45 ; 549 47 ; 549 50 ; 549 52 ; 549 54 ; 549 55 ; 549 61 ; 549 62 ; 549 63 ; 549 64 ; 549 65 ; 549 66 ; 549433 ; 549435 ; 549436 ; 549438 ; 549439 ; 549440 ; 549460 ; 549467 ; 549474 ; 549476 ; 548421 ; 548429 ; 548443 ; 548453 ; 548473 ; 548476 ; 548477 ; 548567 ; 514411 ; 514418 ; 514424 ; 514425 ; 514445 ; 514463 ; 514464 ; 514469 ; 514471 ; 514473 ;
Abstract
The invention concerns heterocyclic nitromethane derivatives of the formula 1 as defined hereinafter (and their non-toxic salts) wherein the heterocyclic moiety Q is thienyl, benzothienyl or dibenzothienyl and may bear a wide variety of optional substituents, together with pharmaceutical compositions containing them. The nitromethane derivatives are inhibitors of the enzyme aldose reductase and are of value in the treatment of certain complications of diabetes and galactosemia.