The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 1992
Filed:
Jan. 18, 1991
Applicant:
Inventors:
Helen H Ong, Whippany, NJ (US);
Gerard J O'Malley, Newtown, PA (US);
Michael C Merriman, Hellertown, PA (US);
Mark G Palermo, Piscataway, NJ (US);
Assignee:
Hoechst-Roussel Pharmaceuticals Inc., Somerville, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142328 ; 514411 ; 544142 ; 544372 ; 546148 ; 546200 ; 548439 ; 548449 ;
Abstract
There are disclosed various compounds of the formula below, ##STR1## where n, X and R.sub.1 through R.sub.4 are as defined in the specification, which are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease. Compound of this invention also inhibit monoamine oxidase and/or act at central .alpha..sub.2 -adrenergic receptors, and hence are useful as antidepressants.