The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 1992

Filed:

Oct. 23, 1990
Applicant:
Inventors:

Michael A Goetz, Fanwood, NJ (US);

Lawrence R Koupal, Colonia, NJ (US);

Cheryl D Schwartz, Westfield, NJ (US);

Jerrold M Liesch, Princeton Junction, NJ (US);

Otto D Hensens, Red Bank, NJ (US);

Paul S Anderson, Lansdale, PA (US);

Roger Freidinger, Hatfield, PA (US);

Douglas J Pettibone, Chalfont, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514-9 ; 530315 ; 530317 ; 530333 ; 514807 ; 435-78 ; 435-71 ; 435 711 ; 435-74 ; 435-76 ; 436501 ;
Abstract

Cyclic peptides are produced by the controlled aerobic fermentation of Streptomyces silvensis, ATTCC No. 53525 or ATCC No. 53526. These compounds are antagonists of oxytocin and are useful in the treatment of preterm labor and vasopressin and are thus useful in the treatment and prevention of disease states wherein vasopressin may be involved, for example congestive heart failure, hypertension, edema and hyponatremia.


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