The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 1992
Filed:
Apr. 25, 1990
Applicant:
Inventors:
Michael Rosenblatt, Ardmore, PA (US);
Eliahu Roubini, Lensvale, PA (US);
Michael Chorev, Jerusalem, IL;
Ruth F Nutt, Green Lane, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
435-721 ; 435-723 ; 435-72 ; 435-40 ; 514 12 ; 530324 ; 530325 ; 930D / ; 930D / ;
Abstract
The present invention relates to the use of peptide hormone analogues as inhibitors of their respective naturally occurring peptide hormone. The structure of the peptide hormone analogues is exemplified by parathyroid hormone (PTH), wherein Lys.sup.13 is substituted to increase the biological activity of the PTH analogues. Thus, there are disclosed peptides having the formulae: