The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 1992

Filed:

Feb. 26, 1988
Applicant:
Inventors:

James A Raleigh, Edmonton, CA;

Gerald G Miller, Edmonton, CA;

Allan J Franko, Edmonton, CA;

J D Chapman, Edmonton, CA;

Assignee:

Alberta Cancer Board, Edmonton, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514398 ; 514-2 ; 514 23 ; 514 44 ; 514558 ; 536-11 ; 536 27 ;
Abstract

A process for preparing an immunogenic conjugate of a nitroaromatic compound and a carrier comprises colavently bonding the nitroaromatic compound to the carrier in an essentially oxygen-free atmosphere and isolating the conjugate from the reaction mixture. The conjugate may be used to raise antibodies specific to the nitroaromatic hapten. The antibodies may be used to determine the presence of hypoxic tissue in living matter by treating the living matter with a nitroaromatic compound and subsequently testing suspected tissue to determine if there is binding of the antibody to tissue. By use of appropriate markers, bound antibodies can be determined to indicate the presence of hypoxic tissue due to the unique reaction of nitroaromatic compounds with hypoxic tissue.


Find Patent Forward Citations

Raleigh, James. (1992). Immunochemical detection of hypoxia in normal and tumor tissue (U.S. Patent No. 5086068). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5086068

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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