The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 1992
Filed:
May. 31, 1989
Applicant:
Inventors:
Toru Kita, Kyoto, JP;
Shuh Narumiya, Kyoto, JP;
Masayuki Narisada, Ibaraki, JP;
Fumihiko Watanabe, Kitakatsuragi, JP;
Saichi Matsumoto, Ikeda, JP;
Masami Doteuchi, Hirakata, JP;
Assignee:
Shionogi & Co., Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08H / ;
U.S. Cl.
CPC ...
260399 ; 514824 ; 568 38 ; 568 54 ; 568 67 ;
Abstract
Phenolic thioethers of the formula: ##STR1## wherein R is a hydrogen atom or a protective group for carboxyl, X is a straight or branched C.sub.4 -C.sub.15 alkylene group, a straight or branched C.sub.1 -C.sub.15 alkylene group having a phenylene group or a straight or branched C.sub.2 -C.sub.15 alkenylene group, and their salts, which inhibit the denaturation of low density lipoproteins (LDL) and the incorporation of LDL by macrophages and are useful as anti-arteriosclerosis agents.