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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5082772 B1

PDFFull Text
Date of Patent:
Jan. 21, 1992

Filed:

Oct. 24, 1988

Process for preparing deacetylcephalosporin c

Applicant:
Inventors:

Joe E Dotzlaf, Greenwood, IN (US);

Wu-Kuang Yeh, Greenwood, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:

Scasnlon; William B.

Whitaker; Leroy

Primary Examiner:

Douglas W Robinson

Assistant Examiner:

Michael V Meller

Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 49 ; 435189 ; 435231 ; 435886 ; 424 946 ;
Abstract

Deacetoxycephalosporin C synthase obtained from cell-free extracts of Streptomyces clavuligerus was purified to near homogeneity and characterized in inactive form. The amino acid sequence was determined and the synthase recombinantly reproduced in active form in E. coli. The recombinantly produced synthase is provided in about 97% pure form by a chromatographic process. The synthase lacks DAOC hydroxylase function; however, it possesses the ability to transform 3-exomethylenocephalosporin C to deacetylcephalosporin C.

Find Patent Forward Citations

Dotzlaf, Joe. (1992). Process for preparing deacetylcephalosporin c (U.S. Patent No. 5082772). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5082772

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