The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 1992
Filed:
Feb. 28, 1990
Applicant:
Inventors:
Jay A Berzofsky, Bethesda, MD (US);
Charles DeLisi, Bethesda, MD (US);
Hanah Margalit, Rockville, MD (US);
James L Cornette, Ames, IA (US);
Kemp B Cease, Rockville, MD (US);
Cecilia S Ouyang, Silver Springs, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
530324 ; 530327 ; 530326 ; 530325 ; 530350 ; 514-2 ; 514-8 ; 514 10 ; 514 14 ; 514 13 ; 514 12 ; 514 21 ; 424 88 ;
Abstract
This invention relates to the identification of short peptide segments of AIDS virus proteins which elicit T cellular immunity, and to a method of inducing cellular immunity to native proteins of the AIDS virus by immunization with short synthetic peptides. Five potential peptides have been identified by searching for regions which can fold as a maximally amphipathic helix. These may be useful to include in either a synthetic peptide- or recombinant fragment- based vaccine.