The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 1992
Filed:
Mar. 01, 1991
Applicant:
Inventors:
Lachlan MaClean, Nottinghamshire, GB;
David L Roberts, Nottinghamshire, GB;
Kenneth Barron, Tyne and Wear, GB;
Kenneth J Nichol, Nottinghamshire, GB;
Albert E Harrison, Nottinghamshire, GB;
Assignee:
The Boots Co. PLC, Nottingham, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514629 ; 514312 ; 546153 ; 546155 ; 546156 ; 564218 ;
Abstract
A process to prepare compounds of formula I ##STR1## in which n=0, 1 or 2 comprising the cyclization of compounds of formula II ##STR2## in which n=0, 1 or 2. The cyclization may be effected in the presence of an organic or inorganic base or thermally at a temperature in the range 40.degree.-160.degree. C. Compounds of formula II and certain analogues thereof are disclosed as cardiovascular agents.