The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 1992
Filed:
Jun. 29, 1988
Applicant:
Inventors:
John D Clements, New Orleans, LA (US);
Sawsan E El-Morshidy, Metarie, LA (US);
Assignee:
Praxis Biologics, Inc., Rochester, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07H / ; C07K / ;
U.S. Cl.
CPC ...
4352528 ; 4351723 ; 435 91 ; 4353201 ; 435879 ; 424 93 ; 424 92 ; 536 27 ; 935 12 ; 935 29 ; 935 72 ; 530403 ;
Abstract
Methods and compositions are provided for the cloning and expression of plasmids bearing genes coding for the non-toxic subunit of the heat-laible enterotoxin (LT-B) of E. coli. These plasmids may be cloned into stable avirulent strains of Salmonella typhi and used to make oral bivalent vaccines. Such vaccines may be used to prevent typhoid fever and cholera-like enterotoxin-induced diarrheal disease.