The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 1992
Filed:
Apr. 04, 1989
Applicant:
Inventors:
Claudio Fuganti, Milan, IT;
Eva Baldaro, Milan, IT;
Daniela Faiardi, Pavia, IT;
Ameriga Lazzarini, Uboldo, IT;
Assignee:
Sclavo S.p.A., Siena, IT;
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435 47 ; 435 43 ; 435 44 ; 435 45 ; 435 46 ; 435 48 ; 435 49 ; 435 50 ; 435 51 ; 435230 ;
Abstract
The present invention relates to a new method of protection of the carboxy group in the chemistry of the compounds of .beta.-lactam type. According to such a method, the carboxy group is protected by being transformed into its corresponding phenyl-acetoxy-methyl ester, which is then removed by an enzymatic route by means of penicillinacylase. In particular, if the .beta.-lactam compound also bears a phenyl-acetamidic substitutent, this latter is simultaneously hydrolysed during the same step of removal of the carboxy function protecting group.