The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 1991
Filed:
Mar. 18, 1991
Applicant:
Inventors:
Keith C Murdock, Pearl River, NY (US);
Ving J Lee, Monsey, NY (US);
Assignee:
American Cyanamid Company, Stamford, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07F / ;
U.S. Cl.
CPC ...
514 94 ; 514397 ; 548111 ; 548336 ;
Abstract
The N-phosphorylation of basic nitrogenous drug compounds to produce pro-drugs with enhanced water solubility or lipid solubility, or reduced toxicity, is disclosed. Drugs containing amine, amidine, quanidine, isourea, isothiourea and biguanide functions may be converted to such pro-drugs. The pro-drugs are hydrolyzed in the body, regenerating the original drugs with the release of a salt of phosphoric acid.
Quick Actions:
Murdock, Keith. (1991). Solubilized imidazole pro-drugs (U.S. Patent No. 5077283). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5077283
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile