The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 1991

Filed:

Jun. 28, 1990
Applicant:
Inventors:

Fahimeh Zarrin, St. Paul, MN (US);

Stanley L Kaufman, Minneapolis, MN (US);

Frank D Dorman, Golden Valley, MN (US);

Assignee:

TSI Incorporated, St. Paul, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
73 6 / ; 73 53 ;
Abstract

An apparatus and method for determining the concentration of macromolecules and colloids in a liquid sample is disclosed. The apparatus preferably includes an electrospray apparatus 16 for forming droplets from the sample. Liquid is removed from the droplets by drying in the electrospray apparatus 16, thereby forming an aerosol. The aerosol of a size greater than a predetermined size is then counted by a condensation nucleus counter 52. In this manner, the target macromolecules and colloids are counted. This apparatus is capable of detecting very small macromolecules and colloids of a wide range of materials in a liquid, for example, individual molecules having molecular weight as small as 10,000.


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