The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 1991

Filed:

Mar. 16, 1990
Applicant:
Inventors:

Shigeru Souda, Ushiku, JP;

Naoyuki Shimomura, Ibaraki, JP;

Norihiro Ueda, Ibaraki, JP;

Shuhei Miyazawa, Ibaraki, JP;

Takashi Yamanaka, Ibaraki, JP;

Kaname Miyamoto, Ibaraki, JP;

Ieharu Hishinuma, Moriyamachi, JP;

Junichi Nagakawa, Ibaraki, JP;

Naoko Nagaoka, Ibaraki, JP;

Hidetoshi Kawashima, Toride, JP;

Tsutomu Kawata, Tsuchiura, JP;

Junsaku Nagaoka, Ibaraki, JP;

Tsuneo Wakabayashi, Mito, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ;
U.S. Cl.
CPC ...
514535 ; 514540 ; 514634 ; 546220 ; 548473 ; 548478 ; 548547 ; 560 34 ; 564104 ; 568 77 ;
Abstract

A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula:


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