The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 1991
Filed:
Apr. 06, 1990
Applicant:
Inventors:
Ian A Cliffe, Slough, GB;
Howard L Mansell, Burnham, GB;
Richard S Todd, Burnham, GB;
Alan C White, Englefield Green, GB;
Assignee:
John Wyeth & Brother Limited, Maidenhead, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514218 ; 514312 ; 514313 ; 514314 ; 514311 ; 540597 ; 546 16 ; 546 21 ; 546 23 ; 546153 ; 546155 ; 546157 ; 546159 ; 546171 ; 546175 ; 546176 ; 546177 ; 546179 ; 546180 ;
Abstract
Pyridine derivatives of formula ##STR1## their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0, 1 and 2 and R, R.sup.1, R.sup.2 and R.sup.2 have specified meanings. The compounds exhibit activity as 5-HT.sub.1A agonists, antagonists or partial agonists and are useful for the treatment of CNS disorders e.g. anxiety, as antihypertensives and in treating anorexia.